Initial data support zinc supplementation for acne vulgaris, hidradenitis suppurativa
Synopsis:
“Zinc appears to have several lines of anti-inflammatory action that involve both adaptive and innate immunity and has been shown to decrease neutrophil chemotaxis, inhibit T helper-17 cell activity and downregulate the expression of Toll-like receptor-2 from keratinocytes,” Raja K. Sivamani, MD, MS, CAT, of the department of dermatology at University of California-Davis, and colleagues wrote.
Link to Article:
Effects of Zinc Supplementation on Inflammatory Skin Diseases: A Systematic Review of the Clinical Evidence
Synopsis:
Some preliminary evidence supports the use of zinc in the treatment of acne vulgaris and hidradenitis suppurativa; however, more research is needed with similar methodologies and larger sample sizes in these diseases. Further, zinc may be of some benefit in the treatment plan for atopic dermatitis and diaper dermatitis; however, additional studies should be conducted to further evaluate these potentially positive associations. To date, no evidence is available to suggest that zinc may be of benefit in rosacea and psoriasis; however, limited data are available evaluating the use of zinc in these conditions.
Link to Article:
https://link.springer.com/article/10.1007/s40257-019-00484-0