Synopsis: Latent tuberculosis infection screening in patients with hidradenitis suppurativa who are treated with TNF alpha inhibitors may be unnecessary, according to a letter published in the Journal of […]
Subject: Treatment & Procedure
Reduced risk of suicidal behaviors with tumor necrosis factor (TNF) alpha antagonists
Synopsis: Background: Hidradenitis suppurativa (HS) is a chronic, recurrent condition that presents as painful, suppurating lesions in the apocrine gland-bearing skin regions. HS has been associated with increased […]
New Minimally Invasive Treatment for Pediatric Patients with HS
Pediatric Endoscopic Hidradenitis Treatment: A New Minimally Invasive Treatment for Pediatric Patients with HS Note: Pediatric HS is not ‘infrequent,’ just incredibly misdiagnosed and under-reported. https://www.ncbi.nlm.nih.gov/m/pubmed/32017645/?i=2&from=hidradenitis
Paradoxical reactions under TNF-α blocking agents and other biological agents
Synopsis: Paradoxical adverse events (PAEs) have been reported during biological treatment for chronic immune-mediated diseases. PAEs are defined as the occurrence during biological agent therapy of a pathological condition […]
Long-Term Safety of Adalimumab
Long-Term Safety of Adalimumab in 29,967 Adult Patients From Global Clinical Trials Across Multiple Indications: An Updated Analysis Synopsis: Introduction: The safety profile of adalimumab was previously reported […]
Adalimumab Dose Intensification in Recalcitrant HS
Synopsis: Background: Adalimumab is the only approved compound for the treatment of adult patients with moderate-to-severe hidradenitis suppurativa (HS) who did not respond to a systemic classical treatment. Despite […]
Infliximab every 4 weeks may be beneficial in treatment
Synopsis: Infliximab maintenance therapy could reduce pain and disease activity in hidradenitis suppurativa, according to a study published in Journal of the American Academy of Dermatology. “Physicians should […]
Current Understanding of Pathogenic Mechanisms and Suggestion for Treatment Algorithm
Synopsis: Hidradenitis suppurativa is one of the most distressing dermatological conditions and has a significant negative impact on patients’ quality of life. However, the exact pathogenic mechanisms remain incompletely […]
Bermekimab Shows Resolution of Inflammatory Lesions and Pain
Synopsis: The objective of this study was to evaluate the safety and efficacy of bermekimab, an IL-1α inhibitor, in the treatment of hidradenitis suppurativa (HS). This study was […]
Absence of efficacy of oral isotretinoin
Absence of efficacy of oral isotretinoin in hidradenitis suppurativa: a retrospective study based on patients’ outcome assessment Synopsis: Background: In analogy to acne, oral isotretinoin has been considered in […]
Clinical characteristics and determinants of treatment efficacy
Synopsis: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder that causes a significant decline in quality of life. There are numerous treatment options; however, real-life data on the […]
20 women treated with spironolactone
Synopsis: Hidradenitis suppurativa (HS) is an uncommon chronic skin condition that can range in severity from a single nodule to extensive disease and can have a profound effect on […]