The bacteriology of hidradenitis suppurativa: a systematic review
Synopsis:
Included studies in the review
A total of 66 papers were identified and nine papers published between 1988 and 2014 matched the above-mentioned inclusion criteria (Fig. 1), yielding bacteriological data of a total of 324 patients with HS (mean age 36.8 years and female/male ratio 215/109).
Microbiological methods used in the included studies
As shown in Table S1, traditional microbiological techniques for culturing bacteria in aerobic and anaerobic environment have been applied to investigate the bacteriology of HS in eight of nine included studies. Three studies used biochemical tests and only one study used immunological identification technique (Lancefield group antigens). One study applied 16S gene ribosomal RNA gene sequencing along with metagenomics. Lastly, only one study investigated the bacteriology in blood samples in patients with HS using PCR (polymerase chain reaction) and DNA sequencing and analysis 24.
The Spectrum of Bacteria found in patients with HS
As displayed in Fig. 2, CoNS (34.1%) and mixed anaerobic bacteria (23.3%) are the most frequently encountered types of bacteria among the 324 patients. In addition, S. aureus also constitutes a considerable part of the overall isolated bacterial specimens (isolated in six of nine studies), and among the studies that identified S. aureus, the prevalence rate ranged from 13% to 56% (Table 1).
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